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KMID : 0606620080040010037
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Korean Journal of Fetal Medicine
2008 Volume.4 No. 1 p.37 ~ p.42
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A Case of Acute Fatty Liver of Pregnancy
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Moon Jeong-Min
Kim Yeon-Hee
Shin Ok-Ran
Lee Hee-Joong
Park Tae-Chul
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Abstract
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We experienced of a case report about acute fatty liver in pregnancy, with liver dysfunction slowly returning to normal after delivery. The case of 32-year-old woman primigravida with acute fatty liver in last trimester of pregnancy is presented with a review of literature and discussion of its origin. The diagnosis of acute fatty liver was suggested by the clinical and laboratory findings of prodromal as general malaise, anorexia and jaundice before the delivery and the rapid onset of deeply jaundice developed with elevated bilirubin and liver enzymes in early postpartum period. Acute fatty liver of pregnancy is a rare condition and serious maternal illness that occurs in third trimester or early postpartum period with significant perinatal and maternal mortality. Early diagnosis followed by prompt delivery and supportive care provides significantly improved maternal and perinatal outcome but delay in diagnosis of this obstetric emergency may lead to rapid progression to hepatic failure, disseminated intravascular coagulation, haemorrhage, encephalopathy, multiple organ failure and finally death.
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KEYWORD
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Acute fatty liver, Liver dysfunction, Maternal outcome
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